Triterpenes, steroids and lichexantone from Macrolobium acaciifolium leaves and branches hexane extracts and antibacterial activity

Macrolobium acaciifolium belongs to Fabaceae family and only few phytochemical studies were carried out in the scientific literature consulted. The objective of this work was isolate identify secondary metabolites from M. leaves branches hexane extracts, addition evaluate antibacterial potential extracts. plant materials dried extracted with hexane, then methanol water. extracts showed presence terpenoids (including steroids) by thin layer chromatography nuclear magnetic resonance analysis. fractionation allowed triterpenes: lupeol, β-amyrin 24-methylenecycloartanol extract. mixture triterpene friedelin xanthone 1-hydroxy-3,6-dimethoxy-8-methyl-9h-xanthen-9-one (lichexanthone) isolated In both steroids β-sitosterol stigmasterol also isolated. extract be toxic Aeromonas hydrophila 87% growth inhibition at a concentration 1000 µg/mL. This is first description isolation these substances activity.